The story
Blend of Deku (でく, alternate kun'yomi reading of 出久 Izuku, homophonous with 木偶) and Melissa.
Etymology from Wiktionary, CC BY-SA 4.0.
DekuMeli
Today it means: The ship of characters Izuku "Deku" Midoriya and Melissa Shield from the My Hero Academia series. Full definition →