The story
From the initials of the surnames of two sisters who had five sons with the syndrome.
Etymology from Wiktionary, CC BY-SA 4.0.
Today it means: A rare genetic disorder linked to the X chromosome, causing physical anomalies and developmental delays, characterised by retardation, hyperactive behaviour, constipation, hypotonia, and a characteristic facial appearance. Full definition →
From the initials of the surnames of two sisters who had five sons with the syndrome.
Etymology from Wiktionary, CC BY-SA 4.0.