Etymology

I've never heard it called that before

Today it means: Used to draw attention to a possible, and usually unintentional, double entendre in the immediately preceding utterance of another speaker. Full definition →

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The story

The word "it" refers to a sex act, bodily organ, etc. for which the speaker's phrase might be construed as a euphemism.

Etymology from Wiktionary, CC BY-SA 4.0.