Nostradamus · proper noun1
Michel de Nostredame's surname is one that honors Saint Mary (Our Lady). More details (if desired) are available at Nostradamus § Childhood.
Nostradamus · noun2
Since before 1908. Most likely from wordplay among physicians, as a playful agent noun for quacks who give nostrums to their patients, playing on wide familiarity with a cultural reference to the famous (and dubiously effective) Nostradamus.
Etymology from Wiktionary, CC BY-SA 4.0.