The story
After Shakespeare's character Othello, who kills his lover after becoming falsely convinced that she is unfaithful.
Etymology from Wiktionary, CC BY-SA 4.0.
Today it means: delusional jealousy; a psychiatric disorder in which a person holds a strong delusional belief that their spouse or sexual partner is being unfaithful Full definition →
After Shakespeare's character Othello, who kills his lover after becoming falsely convinced that she is unfaithful.
Etymology from Wiktionary, CC BY-SA 4.0.