enchiridion

The story

1. Ancient Greek · borrowed fromἐγχειρίδιον“handbook, manual”
2. Latin · borrowed fromenchīridion
3. English todayenchiridion

Either via Latin enchīridion or directly, from Ancient Greek ἐγχειρίδιον (enkheirídion, “handbook, manual”), from ἐν (en, “in”) + χείρ (kheír, “hand”) + -ίδιον (-ídion).