Etymology

fly off the handle

Today it means: To become very angry or enraged; to throw a fit or go crazy. Full definition →

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The story

From the image of an axe head becoming loose and suddenly flying free of its handle, a vivid metaphor for losing control. The phrase is an early 19th-century American idiom, with printed examples first appearing c. the 1810s–1830s.

Etymology from Wiktionary, CC BY-SA 4.0.