Etymology

ham-fisted

ham-fist·ed

Today it means: Lacking skill in physical movement with the hands; clumsy. Full definition →

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The story

From ham (“thigh and buttock of an animal slaughtered for meat”) + fisted (adjective), probably referring to someone being clumsy as if they have hams at the end of their arms instead of hands.

Etymology from Wiktionary, CC BY-SA 4.0.