Etymology

hardware disease

Today it means: Traumatic gastrointestinal puncture and infection in ruminants (especially cattle) and birds that ingest a sharp object (in livestock usually a metal object such as wire or a fastener); in cattle it usually includes reticuloperitonitis and thus in practice is usually metonymically synonymous with traumatic reticuloperitonitis. Full definition →

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The story

From the fact that in cattle it is usually caused by hardware such as a piece of wire or a fastener (e.g., fence wire, nail, screw).

Etymology from Wiktionary, CC BY-SA 4.0.