Etymology

homie

hom·ie
H4O1M3I1E1

Today it means: Someone, particularly a friend or male acquaintance, from one's hometown. Full definition →

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The story

Earliest known reference is in the tune The House of Blue Lights (1946) by Ella Mae Morse and Freddie Slack, when Morse improvises a spoken-word intro. Equivalent to home + -ie.

Etymology from Wiktionary, CC BY-SA 4.0.