Etymology

lionitis

L1I1O1N1I1T1I1S1

Today it means: craniodiaphyseal dysplasia: a rare autosomal-recessive bone disorder that causes calcium to build up in the skull, disfiguring the facial features and reducing life expectancy Full definition →

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The story

From lion + -itis, from the leonine facial appearance in some cases.

Etymology from Wiktionary, CC BY-SA 4.0.