Etymology

mayapple

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Today it means: A fruit-bearing flowering plant with poisonous roots, native to eastern North America, taxonomic name Podophyllum peltatum. Full definition →

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The story

From May + apple. The fruit is notably neither related to apples (though "apple" itself has an archaic sense of generically referring to fruit), nor ripens during the month of May; only the flower blooms then around then in certain areas.

Etymology from Wiktionary, CC BY-SA 4.0.