Etymology

misfold

M3I1S1F4O1L1D2

Today it means: To fold into an unusual or incorrect tertiary structure; misfolded proteins occur in various diseases, including amyloidoses and dementias, although the question of causation versus consequence is not yet definitively answered for dementias. Full definition →

English fold ← Middle English mys- ← Old English mis-
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The story

  1. Proto-Indo-European*mey-?
  2. Proto-Indo-European*meyth₂-
  3. Proto-Germanic*missaz
  4. Proto-Germanic*missa-
  5. Proto-West Germanic*missa-
  6. Old Englishmis-
  7. Middle Englishmys-
  8. Englishmis-
  9. Englishfold
  10. English todaymisfold

From mis- + fold.

Etymology from Wiktionary, CC BY-SA 4.0.