nonspirituous

The story

1. Proto-Indo-European*né
2. Proto-Germanic*ne
3. Proto-Indo-European*ís?
4. Proto-Indo-European*h₁óynos
5. Proto-Germanic*ainaz
6. Proto-Germanic*nainaz
7. Proto-West Germanic*nain
8. Old Englishnān
9. Middle Englishnon
10. Old Englishnān
11. Old Englishnān-
12. Middle Englishnon-
13. Englishnon-
14. Proto-Indo-European*(s)peys-der.?
15. Latinspīrō
16. Latinspīritus
17. Proto-Indo-European*h₃ed-
18. Proto-Indo-European*h₃édosder.?
19. Medieval Latinspīrituōsus
20. Englishspirituous
21. English todaynonspirituous

From non- + spirituous.