Etymology

noseeum

no·see·um
N1O1S1E1E1U1M3

Today it means: A biting midge, a small flying insect that harasses people outdoors, particularly in warm weather after sunset. Full definition →

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The story

A shortening of earlier no-see-um, a univerbation of no (“not, don't, cannot”) + see (“to perceive visually”) + um (alternative form of 'em, third-person singular/plural indicative pronoun).

Etymology from Wiktionary, CC BY-SA 4.0.