Etymology

per vaginam

Today it means: Through the vagina, as (usually, more specifically) by the vaginal route of administration. Full definition →

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The story

Naturalized into medical English from neoclassical use of Latin in the professions. Exists in loanword form (retaining the Latin inflection, -am) and also in a further naturalized form with reanalysis in English morphology, per vagina = per + vagina, in parallel with other per + [English noun] constructions, such as per instructions or per statute.

Etymology from Wiktionary, CC BY-SA 4.0.