The story
- Proto-West Germanic · inherited from*twekkōn“to fasten; clamp; pinch”
- Old English · inherited fromtwiccian“to pluck”
- Middle English · inherited fromtwikken
- English todaytweak
From Middle English twikken, from Old English twiccian (“to pluck”), from Proto-West Germanic *twekkōn (“to fasten; clamp; pinch”). Related to twitch. The drug-related sense may be a blend of twitch and freak.
Etymology from Wiktionary, CC BY-SA 4.0.