Alexander's disease

A form of Alexander disease — A rare, progressive, and usually fatal neurological disorder; classified as a leukodystrophy, it is fundamentally a disease of the brain’s astrocytes; caused by genetic mutations that lead to the abnormal accumulation of proteins, known as Rosenthal fibers, which destroy the protective myelin sheath in the central nervous system.

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Meanings

nounAlexander's disease (uncountable)
  1. alternativeuncountableAlternative form of Alexander disease.
Cite this entry
APA

Alexander's disease. (n.d.). In WatkinsX Dictionary. Retrieved November 5, 2026, from https://dictionary.watkinsx.com/word/Alexander's%20disease

MLA

“Alexander's disease.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/Alexander's%20disease. Accessed November 5, 2026.

Chicago

WatkinsX Dictionary, s.v. “Alexander's disease,” accessed November 5, 2026, https://dictionary.watkinsx.com/word/Alexander's%20disease.

Source: Alexander's disease on Wiktionary, CC BY-SA 4.0.