Meckel-Gruber syndrome

noun

A rare, lethal ciliopathic genetic disorder characterized by renal cystic dysplasia, central nervous system malformations (occipital encephalocele), polydactyly (postaxial), hepatic developmental defects, and pulmonary hypoplasia due to oligohydramnios.

Similar
dysencephalia splanchnocysticaMeckel syndrome
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Meanings

nounMeckel-Gruber syndrome (uncountable)
  1. uncountableA rare, lethal ciliopathic genetic disorder characterized by renal cystic dysplasia, central nervous system malformations (occipital encephalocele), polydactyly (postaxial), hepatic developmental defects, and pulmonary hypoplasia due to oligohydramnios.

    Synonyms: dysencephalia splanchnocystica, Meckel syndrome

Synonyms & antonyms

nounA rare, lethal ciliopathic genetic disorder characterized by renal cystic dysplasia, central nervous system malformations (occipital encephalocele), polydactyly (postaxial), hepatic developmental defects, and pulmonary hypoplasia due to oligohydramnios.

Similar
dysencephalia splanchnocysticaMeckel syndrome
Also see
meckel syndrome

Origin

Named after Johann Meckel and Georg Gruber.

Full word history & related roots →
Cite this entry
APA

Meckel-Gruber syndrome. (n.d.). In WatkinsX Dictionary. Retrieved November 5, 2026, from https://dictionary.watkinsx.com/word/Meckel-Gruber%20syndrome

MLA

“Meckel-Gruber syndrome.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/Meckel-Gruber%20syndrome. Accessed November 5, 2026.

Chicago

WatkinsX Dictionary, s.v. “Meckel-Gruber syndrome,” accessed November 5, 2026, https://dictionary.watkinsx.com/word/Meckel-Gruber%20syndrome.

Source: Meckel-Gruber syndrome on Wiktionary, CC BY-SA 4.0.