SLE

S1L1E1

A form of systemic lupus erythematosus — A systemic autoimmune disease (or autoimmune connective tissue disease), where the immune system attacks the body's cells and tissue and causes inflammation and tissue damage.

Similar
systemic lupus erythematosusdisseminated lupus erythematosus
Less commonScrabble 3
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Meanings

nounSLE (countable and uncountable, plural SLEs)

plural SLEs

  1. abbreviationcountableinitialismuncountablemedicineInitialism of systemic lupus erythematosus.

    Iberdomide, a cereblon modulator promoting degradation of the transcription factors Ikaros and Aiolos, which affect leukocyte development and autoimmunity, is being evaluated for the treatment of systemic lupus erythematosus (SLE).

    2022 March 17, Joan T. Merrill, Victoria P. Werth, Richard Furie et al., “Phase 2 Trial of Iberdomide in Systemic Lupus Erythematosus”, in The New England Journal of Medicine, volume 386, number 11, →DOI, page 1034
  2. abbreviationcountableinitialismuncountableareologyInitialism of single-layer ejecta.
proper noun
  1. Singaporeabbreviationon road signsAbbreviation of Seletar Expressway.

Synonyms & antonyms

nounan inflammatory disease of connective tissue with variable features including fever and weakness and fatigability and joint pains and skin lesions on the face or neck or arms

Similar
systemic lupus erythematosusdisseminated lupus erythematosus
Broader
lupus
Also see
systemic lupus erythematosus

Synonym sets from Open English WordNet, CC BY 4.0.

Rhymes & wordplay

Anagrams

lesESLSel
Cite this entry
APA

SLE. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/SLE

MLA

“SLE.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/SLE. Accessed November 4, 2026.

Chicago

WatkinsX Dictionary, s.v. “SLE,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/SLE.

Source: SLE on Wiktionary, CC BY-SA 4.0.