SSRI

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A form of selective serotonin reuptake inhibitor — Any of a class of drugs, such as fluoxetine or sertraline, that inhibit the uptake of serotonin in the central nervous system and are often used to treat certain mental illnesses, such as depression.

Similar
selective-serotonin reuptake inhibitor
UncommonScrabble 4

Meanings

nounSSRI (plural SSRIs)

plural SSRIs

  1. abbreviationinitialismmedicineInitialism of selective serotonin reuptake inhibitor.

    Based on previous data, here we sought to test the hypothesis that exposure to SSRIs would alter the proliferation and apoptosis of perisutural cells at the cellular and transcription levels.

    2015 October 3, “Effects of Citalopram on Sutural and Calvarial Cell Processes”, in PLOS ONE, →DOI
    2 more examples

    Considering mental illness an individual chemico-biological problem has enormous benefits for capitalism. First, it reinforces Capital’s drive towards atomistic individualization (you are sick because of your brain chemistry). Second, it provides an enormously lucrative market in which multinational pharmaceutical companies can peddle their pharmaceuticals (we can cure you with our SSRIs).

    2009, Mark Fisher, chapter 5, in Capitalist Realism: Is There No Alternative?, Zero Books, →ISBN, page 36

    Sometimes lowering the SSRI dose a little helps people still do well mentally without having sexual dysfunction, Alpert said. […] Bupropion is more conducive to sexual function because instead of increasing serotonin such as SSRIs do, it ups the amount of dopamine in the brain, which supports sexual desire and response, experts said.

    2024 March 21, Kristen Rogers, “If antidepressants are killing your sex life, here’s what you can do”, in CNN
  2. abbreviationinitialismmedicineInitialism of serotonin-specific reuptake inhibitor.

Synonyms & antonyms

nounan antidepressant drug that acts by blocking the reuptake of serotonin so that more serotonin is available to act on receptors in the brain

Similar
selective-serotonin reuptake inhibitor
Broader
antidepressantantidepressant drug

Synonym sets from Open English WordNet, CC BY 4.0.

Translations

Russian СИОЗС
  • СИОЗС (SIOZS)any of a class of drugs that inhibit the uptake of serotonin in the central nervous system

Rhymes & wordplay

Anagrams

Cite this entry
APA

SSRI. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/SSRI

MLA

“SSRI.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/SSRI. Accessed November 3, 2026.

Chicago

WatkinsX Dictionary, s.v. “SSRI,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/SSRI.

Source: SSRI on Wiktionary, CC BY-SA 4.0.