acanthosis nigricans

US/æˌkænˈθoʊ.sɪs/US/ˈnɪɡ.ɹɪˌkænz/US/ˈnaɪɡ.ɹɪˌkænz/

noun

A skin sign often associated with insulin resistance and type 2 diabetes exhibiting velvety, thickened, and darkened skin and skin tags, often occurring in skin folds and the axillae.

Similar
keratosis nigricans

Meanings

nounacanthosis nigricans (uncountable)
  1. uncountablemedicineA skin sign often associated with insulin resistance and type 2 diabetes exhibiting velvety, thickened, and darkened skin and skin tags, often occurring in skin folds and the axillae.

Synonyms & antonyms

nouna skin disease characterized by dark wartlike patches in the body folds; can be benign or malignant

Similar
keratosis nigricans
Broader
skin diseasedisease of the skinskin disorder

Synonym sets from Open English WordNet, CC BY 4.0.

Origin

  1. Latinnigricans“blackish”
  2. Ancient Greekἄκανθος“thorny flower”
  3. Englishacanthosis nigricans

Via Latin ultimately from Ancient Greek ἄκανθος (ákanthos, “thorny flower”) + -ωσις (-ōsis, “state, abnormal condition, or action”) + Latin nigricans (“blackish”).

Full word history & related roots →
Cite this entry
APA

acanthosis nigricans. (n.d.). In WatkinsX Dictionary. Retrieved November 5, 2026, from https://dictionary.watkinsx.com/word/acanthosis%20nigricans

MLA

“acanthosis nigricans.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/acanthosis%20nigricans. Accessed November 5, 2026.

Chicago

WatkinsX Dictionary, s.v. “acanthosis nigricans,” accessed November 5, 2026, https://dictionary.watkinsx.com/word/acanthosis%20nigricans.

Source: acanthosis nigricans on Wiktionary, CC BY-SA 4.0.