atypism

Category 1: mildly distorted glandular structures, branching villi and tubular crypt proliferation, mild nuclear and cellular atypism, and intact basement membrane; Category 2: moderately or severely distorted glandular structures with branching villi, severe nuclear and cellular atypism, increased mitotic figures, increased atypical mucous retention, and intact basement membrane; Category 3: evident infiltration of tumor cell nests with tumor stromal induction, increased mitotic figures, penetration of the basement membrane, and invasion of the lamina propria or muscularis mucosae.

2015 July 28, Masayuki Tsuneki et al., “Mieap suppresses murine intestinal tumor via its mitochondrial quality control”, in Scientific Reports, volume 5, →DOI