bandshift assay

noun

A type of assay using gel electrophoresis, in which the mobility of a DNA or RNA probe alone is compared to its mobility in combination with a particular protein, so as to measure the degree and nature of binding between the protein and DNA or RNA.

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Meanings

nounbandshift assay (plural bandshift assays)

plural bandshift assays

  1. biochemistryA type of assay using gel electrophoresis, in which the mobility of a DNA or RNA probe alone is compared to its mobility in combination with a particular protein, so as to measure the degree and nature of binding between the protein and DNA or RNA.

    In bandshift assays, hPot1p bound to the G-rich strand of human telomeric DNA.

    2001 May 11, Peter Baumann, Thomas R. Cech, “Pot1, the Putative Telomere End-Binding Protein in Fission Yeast and Humans”, in Science, volume 292, number 5519, →DOI, pages 1171–1175
Cite this entry
APA

bandshift assay. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/bandshift%20assay

MLA

“bandshift assay.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/bandshift%20assay. Accessed November 4, 2026.

Chicago

WatkinsX Dictionary, s.v. “bandshift assay,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/bandshift%20assay.

Source: bandshift assay on Wiktionary, CC BY-SA 4.0.