Meanings
- uncountablemedicineAn experimental medication belonging to the class of Janus kinase inhibitors.
1 more example
Developed to target the kinase domain of JAK3, decernotinib (VX-509) showed selective in vitro inhibition of JAK3 over the other JAKs and efficacy in RA (73, 74). However, a CYP3A4-mediated drug–drug interaction was also described, potentially limiting the use of decernotinib; development of this molecule has currently been halted (75).
2021 December, Christine Liu, Jacqueline Kieltyka, Roy Fleischmann, Massimo Gadina, John J. O’Shea, “A Decade of JAK Inhibitors: What Have We Learned and What May Be the Future?”, in Arthritis & Rheumatology, volume 73, number 12, →DOI, page 2172
Cite this entry
decernotinib. (n.d.). In WatkinsX Dictionary. Retrieved November 2, 2026, from https://dictionary.watkinsx.com/word/decernotinib
“decernotinib.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/decernotinib. Accessed November 2, 2026.
WatkinsX Dictionary, s.v. “decernotinib,” accessed November 2, 2026, https://dictionary.watkinsx.com/word/decernotinib.
Source: decernotinib on Wiktionary, CC BY-SA 4.0.