decompensation

plural decompensations

1. countableuncountablemedicineThe inability of a diseased or weakened organic system or organ to compensate for its deficiency, resulting in functional deterioration.

   Once it was determined that hyperthyroidism was the probable etiology of her cardiac decompensation, the next step was treatment of the underlying disease.

   1982, Pamela Martyn, “If You Guessed Cardiovascular Disease, Guess again”, in American Journal of Nursing, volume 82, number 8, page 1239

2. countableuncountablehuman sciencesThe deterioration of cognitive or emotional functionality in a person who is distressed or who suffers from a psychological disorder.

   A varying percentage of our combat soldiers reach the limit of their endurance and must leave their foxholes, not for physical wounds but because of emotional decompensation.

   1945 May, William C. Menninger, “The Mentally or Emotionally Handicapped Veteran”, in Annals of the American Academy of Political and Social Science, volume 239, page 21