Meanings
adjectivedefucosylated (not comparable)
- not comparableHaving undergone defucosylation.
It was previously reported that the lack of the core fucose from Fc N-glycans significantly enhances ADCC activity compared to defucosylated and conventional mAbs, and we observed this phenomenon for both SKBR-3 and BT-474 cells, excluding aglycosylated mAbs (mAb-PNGF).
2015 July 23, “Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities”, in PLOS ONE, →DOI
Cite this entry
APA
defucosylated. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/defucosylated
MLA
“defucosylated.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/defucosylated. Accessed November 4, 2026.
Chicago
WatkinsX Dictionary, s.v. “defucosylated,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/defucosylated.
Source: defucosylated on Wiktionary, CC BY-SA 4.0.