demethylate

D2E1M3E1T1H4Y4L1A1T1E1
UK/diːˈmɛθəleɪt/

verb

To remove one or more methyl groups from a molecule, especially from a biologically active molecule

Scrabble 20

Meanings

verbdemethylate (third-person singular simple present demethylates, present participle demethylating, simple past and past participle demethylated)

present singular third person demethylates · participle present demethylating · participle past demethylated · past demethylated

  1. biochemistryTo remove one or more methyl groups from a molecule, especially from a biologically active molecule

Origin

  1. Proto-Indo-European*de
  2. Proto-Indo-European*déh₁
  3. Proto-Italic*dē
  4. Latindē
  5. Latindē-
  6. Englishde-
  7. Englishmethylate
  8. Englishdemethylate

From de- + methylate.

Full word history & related roots →

Translations

Catalan desmetilar
  • desmetilarto remove methyl groups
Russian деметилировать
  • деметилировать (demetilirovatʹ)to remove methyl groups
Cite this entry
APA

demethylate. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/demethylate

MLA

“demethylate.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/demethylate. Accessed November 3, 2026.

Chicago

WatkinsX Dictionary, s.v. “demethylate,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/demethylate.

Source: demethylate on Wiktionary, CC BY-SA 4.0.