Meanings
- uncountablechemistryThe compound 2-phenyl-1-(2-thiazolyl)ethylamine normally found associated with a dolastatin
We subsequently identified the degradation by mass spectrometry as a loss of 186 Da, which is consistent with the hydrolytic cleavage of the C-terminal dolaphenine residue of MMAD (Fig 2a and 2b, Figs a and b in S1 Fig ).
2015 July 11, “Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy”, in PLOS ONE, →DOI
Cite this entry
dolaphenine. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/dolaphenine
“dolaphenine.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/dolaphenine. Accessed November 4, 2026.
WatkinsX Dictionary, s.v. “dolaphenine,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/dolaphenine.
Source: dolaphenine on Wiktionary, CC BY-SA 4.0.