endoxifen

E1N1D2O1X8I1F4E1N1

noun

A metabolite of tamoxifen, 4-[(Z)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol, that has similar properties

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Meanings

nounendoxifen (uncountable)
  1. uncountableA metabolite of tamoxifen, 4-[(Z)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol, that has similar properties

    It is described as a prodrug since most of its antiestrogen effects are exerted through its hydroxylated metabolites 4-OH-tamoxifen and endoxifen.

    2015 July 16, “Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients”, in PLOS ONE, →DOI
Cite this entry
APA

endoxifen. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/endoxifen

MLA

“endoxifen.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/endoxifen. Accessed November 4, 2026.

Chicago

WatkinsX Dictionary, s.v. “endoxifen,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/endoxifen.

Source: endoxifen on Wiktionary, CC BY-SA 4.0.