herxing

H4E1R1X8I1N1G2

noun

Jarisch–Herxheimer reaction, a negative reaction to antibiotic treatment.

Scrabble 18

Meanings

verb
  1. gerundparticiplepresentpresent participle and gerund of herx (“to experience Jarisch–Herxheimer reaction”)
nounherxing (uncountable)
  1. informaluncountablemedicineJarisch–Herxheimer reaction, a negative reaction to antibiotic treatment.

    He sets the machine to the frequency that’s supposed to kill the Lyme spirochete, turns it on, and immediately starts Herxing.

    2021 December, Sam Kriss, “It’s not all in your head”, in First Things: A Monthly Journal of Religion and Public Life, page 12
    3 more examples

    Brenner’s own experience with “herxing” (a common phrase among Lyme patients) started 2 or 3 hours after his first antibiotic treatment.

    1997 February, Edward McSweegan, “TNF antibodies get new lease”, in Nature Medicine, volume 3, number 2, page 130

    Moreover, the Jarish–Herxheimer reaction (sometimes referred to as “herxing”) is a rare syndrome seen within the first 48 hr of starting antibiotic treatment for some spirochetal diseases; the belief that “herxing” causes ongoing symptom flares in patients with Lyme disease is a fallacy for which there is no objective evidence.

    2013 July, Centers for Disease Control and Prevention, “Article Corrections”, in Gifted Child Today, volume 36, number 3, page 215

    Herxes, or “herxing,” are a great bugbear in the world of chronic Lyme. The term is drawn from the Jarisch-Herxheimer reaction, originally identified in the context of syphilis. It refers to a brief, severe reaction that can take place within the first few days of antibiotic treatment; as bacteria die off and release endotoxins, a patient experiences fever, chills, and sometimes dangerously low blood pressure.

    2019 July 22, Molly Fischer, “Maybe it’s Lyme”, in New York magazine

Origin

Shortened from Jarisch-Herxheimer reaction, which in turn derives from the names of Adolf Jarisch and Karl Herxheimer, physicians who separately described the reaction in syphilis patients.

Full word history & related roots →
Cite this entry
APA

herxing. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/herxing

MLA

“herxing.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/herxing. Accessed November 3, 2026.

Chicago

WatkinsX Dictionary, s.v. “herxing,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/herxing.

Source: herxing on Wiktionary, CC BY-SA 4.0.