Meanings
- pluralplural of heteroduplex
The DGGE technique allows for verification of heteroplasmy through the resolution of mismatch-containing heteroduplices from fully base-paired homoduplices in an increasingly denaturing environment.
2014, Mitchell Holland, Terry Melton, Charity Holland, “Forensic Mitochondrial DNA Analysis: Current Practice and Future Potential”, in Jaiprakash G. Shewale, Ray H. Liu, editors, Forensic DNA Analysis: Current Practices and Emerging Technologies, CRC Press, →ISBN, section IV (Expanding the Genotyping Capabilities), page 2672 more examples
Melting differences of heteroduplices compared to homoduplices are probably influenced by both the mutation and the surrounding sequence, e.g. for the 3905insT-mutation where one additional T is inserted into a stretch of 6 Ts.
2002, S. Kleinle, K. Tabiti, S. Gallati, “Limitations of Melting Curve Analysis Using SYBR Green I – Fragment Differentiation and Mutation Detection in the CFTR-Gene”, in Wolfgang Dietmaier, Carl Wittwer, Natarajan Sivasubramanian, editors, Rapid Cycle Real-Time PCR – Methods and Applications: Genetics and Oncology, Springer-Verlag Berlin Heidelberg New York, →ISBN, part I (Methods Useful in Genetics and Oncology), page 55Because more homoduplices than heteroduplices develop after rehybridization, a rather intense background pattern is obtained from the digested homoduplices, which can cause the interesting bands to disappear.
2007, Cornel Mülhardt, Molecular Biology and Genomics (The Experimenter Series), Academic Press, →ISBN, pages 165–166
Cite this entry
heteroduplices. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/heteroduplices
“heteroduplices.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/heteroduplices. Accessed November 4, 2026.
WatkinsX Dictionary, s.v. “heteroduplices,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/heteroduplices.
Source: heteroduplices on Wiktionary, CC BY-SA 4.0.