histamine

H4I1S1T1A1M3I1N1E1
/ˈhɪstəmiːn/

noun

An amine, C₅H₉N₃, formed by decarboxylation of histidine, that causes dilatation of capillaries, contraction of smooth muscle, and stimulation of gastric acid secretion; it is released during allergic reactions.

Less commonScrabble 14

Meanings

nounhistamine (countable and uncountable, plural histamines)

plural histamines · alternative dated histamin

  1. countableuncountablebiochemistryAn amine, C₅H₉N₃, formed by decarboxylation of histidine, that causes dilatation of capillaries, contraction of smooth muscle, and stimulation of gastric acid secretion; it is released during allergic reactions.

    The intake of food triggers a release of histamine, which activates the acid-secreting cells.

    2001, Leslie Iversen, Drugs: A Very Short Introduction, Oxford, page 46
    2 more examples

    Mellanby and Twort have isolated from the fæces a bacillus which is able to produce from one of the amino acids normally formed in digestion of proteins a highly active body, histamine.

    1913 June 1, Henderson VE, “Res Judicatae: On the Colon and Ileocolotomy”, in The Canadian Medical Association Journal, volume 3, number 6, page 521

    In a strongly ripened cheese, the casein proteins are broken down to amino acids, and the amino acids can be broken down into amines, small molecules that can serve as chemical signals in the human body. Histamine and tyramine are found in large quantities in Cheddar, blue, Swiss, and Dutch-style cheeses, and can cause a rise in blood pressure, headaches, and rashes in people who are especially sensitive to them.

    2004, Harold McGee, chapter 1, in On Food and Cooking: The Science and Lore of the Kitchen, Scribner, →ISBN

Origin

  1. Proto-Indo-European*steh₂-
  2. Ancient Greekῐ̔στός (hĭstós)
  3. Englishhisto-
  4. Englishhist(idine)
  5. Egyptianjmn
  6. Ancient GreekᾸ̓́μμων (Ắmmōn)
  7. LatinAmmōn
  8. Latinammoniacus
  9. Englishammonia
  10. Englishamine
  11. Englishhistamine

From hist(idine) + -amine.

Full word history & related roots →

Translations

Catalan histamina
  • histaminaan amine
Chinese Mandarin 組胺 /组胺
  • 組胺 /组胺 (zǔ'àn)an amine
Czech histamin
  • histaminan amine
Esperanto histamino
  • histaminoan amine
Finnish histamiini
  • histamiinian amine
French histamine
  • histaminean amine
German Histamin
  • Histaminan amine
Greek ισταμίνη
  • ισταμίνη (istamíni)an amine
Hungarian hisztamin
  • hisztaminan amine
Icelandic lostefni, histamín
  • lostefnian amine
  • histamínan amine
Indonesian histamina
  • histaminaan amine
Italian istamina
  • istaminaan amine
Japanese ヒスタミン
  • ヒスタミン (hisutamin)an amine
Korean 히스타민
  • 히스타민 (hiseutamin)an amine
Polish histamina
  • histaminaan amine
Portuguese histamina
  • histaminaan amine
Romanian histamină
  • histaminăan amine
Russian гистами́н
  • гистами́н (gistamín)an amine
Spanish histamina
  • histaminaan amine
Swedish histamin
  • histaminan amine
Turkish histamin
  • histaminan amine
Cite this entry
APA

histamine. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/histamine

MLA

“histamine.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/histamine. Accessed November 3, 2026.

Chicago

WatkinsX Dictionary, s.v. “histamine,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/histamine.

Source: histamine on Wiktionary, CC BY-SA 4.0.