hybridoma

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noun

A hybrid cell engineered from a lymphocyte and a tumour cell; used to generate monoclonal antibodies

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Meanings

nounhybridoma (plural hybridomas or hybridomata)

plural hybridomas · plural hybridomata

  1. immunologyA hybrid cell engineered from a lymphocyte and a tumour cell; used to generate monoclonal antibodies

    Athymic (nude) mice and rats were inoculated intraperitoneally with rat-mouse hybridoma cells secreting monoclonal antibodies to rat MHC class I antigens in order to improve the yield of antibodies.

    1982, Saad A. Noeman, Dhirendra N.Misra, Robert J. Yankes, Heinz W. Kunz, Thomas J. Gill III, “Growth of Rat-mouse hybridomas in nude mice and nude rats”, in Journal of Immunological Methods, →DOI

Origin

From hybrid + -oma.

Full word history & related roots →

Translations

Italian ibridoma
  • ibridomaTranslations
Cite this entry
APA

hybridoma. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/hybridoma

MLA

“hybridoma.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/hybridoma. Accessed November 4, 2026.

Chicago

WatkinsX Dictionary, s.v. “hybridoma,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/hybridoma.

Source: hybridoma on Wiktionary, CC BY-SA 4.0.