Meanings
- uncountablebiologyThe condition of having an enlarged cell nucleus.
In addition, mammary glands in transgenic mice exhivited an increased occurrence of multinucleated cells, and some nuclei were enlarged (karyomegaly), with a hyperchromatic appearance.
1999, Andrea Manni, Endocrinology of Breast Cancer, page 852 more examples
As the cell grows the large size of the nucleus appears to diminish, but in some cases karyomegaly exists, as in the mantle of Zonites, of slugs, and of Prosobranchs, the circumcerebral tissue of snails, and the tissue around the otocyst in Cyclostoma.
1895 April 28, “Connective Cells of Gastropods”, in Journal of the Royal Microscopical Society, volume 15, number 2, page 167For the few chemical compounds where the histogenesis of renal adenocarcinoma has been studied in detail, karyomegaly is often seen as one of the earliest cellular alterations which can be related to carcinogen exposure.
2013, G. W. Richter, International Review of Experimental Pathology: Kidney Disease, page 368Synonyms: cytokaryomegaly
Synonyms & antonyms
nounThe condition of having an enlarged cell nucleus.
Origin
Cite this entry
karyomegaly. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/karyomegaly
“karyomegaly.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/karyomegaly. Accessed November 4, 2026.
WatkinsX Dictionary, s.v. “karyomegaly,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/karyomegaly.
Source: karyomegaly on Wiktionary, CC BY-SA 4.0.