lissencephaly

L1I1S1S1E1N1C3E1P3H4A1L1Y4
/ˌlɪs.ɛnˈsɛf.əl.i/

noun

The condition of having a smooth appearance on the surface of the brain.

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Meanings

nounlissencephaly (uncountable)
  1. uncountableanatomyThe condition of having a smooth appearance on the surface of the brain.
    1. uncountableanatomyAn abnormality of brain development marked by the presence of a smooth cerebral cortex with few or no convolutions; frequently associated with severe developmental disability.

Origin

From Ancient Greek λισσός (lissós, “smooth”) + encephal- (“brain”) + -y, from Ancient Greek ἐν (en, “in”) + κεφαλή (kephalḗ, “head”).

Full word history & related roots →

Translations

Catalan lissencefàlia
  • lissencefàliadisorder characterized by the lack of folds and grooves of the brain
Chinese Mandarin 平腦症 /平脑症
  • 平腦症 /平脑症 (píngnǎozhèng)disorder characterized by the lack of folds and grooves of the brain
Dutch lissencefalie
  • lissencefaliedisorder characterized by the lack of folds and grooves of the brain
Finnish lissenkefalia
  • lissenkefaliadisorder characterized by the lack of folds and grooves of the brain
French lissencéphalie
  • lissencéphaliedisorder characterized by the lack of folds and grooves of the brain
German Lissenzephalie
  • Lissenzephaliedisorder characterized by the lack of folds and grooves of the brain
Italian lissencefalia
  • lissencefaliadisorder characterized by the lack of folds and grooves of the brain
Polish bezzakrętowość
  • bezzakrętowośćdisorder characterized by the lack of folds and grooves of the brain
Portuguese lisencefalia
  • lisencefaliadisorder characterized by the lack of folds and grooves of the brain
Russian лиссэнцефалия
  • лиссэнцефалия (lissɛncefalija)disorder characterized by the lack of folds and grooves of the brain
Spanish lisencefalia
  • lisencefaliadisorder characterized by the lack of folds and grooves of the brain
Turkish kıvrımsız beyin
  • kıvrımsız beyindisorder characterized by the lack of folds and grooves of the brain
Ukrainian лісенцефалія
  • лісенцефалія (lisencefalija)disorder characterized by the lack of folds and grooves of the brain

Rhymes & wordplay

Rhymes with lissencephaly

microcephalyanencephalyholoprosencephalyacephaly-cephalydicephalymacrocephalymegalocephaliamegalocephalyplagiocephalytrigonocephaly
All rhymes →
Cite this entry
APA

lissencephaly. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/lissencephaly

MLA

“lissencephaly.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/lissencephaly. Accessed November 4, 2026.

Chicago

WatkinsX Dictionary, s.v. “lissencephaly,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/lissencephaly.

Source: lissencephaly on Wiktionary, CC BY-SA 4.0.