methylenetetrahydrofolatereductase

me·thyl·ene·te·tra·hy·dro·fo·late·re·duct·ase
UK/ˌmɛ.θɪ.liːnˌtɛ.tɹəˌhʌɪ.dɹə(ʊ)ˌfəʊ.leɪt.ɹɪˈdʌk.teɪz/US/ˌmɛ.θə.liːnˌtɛ.tɹəˌhaɪ.dɹəˌfoʊ.leɪt.ɹɪˈdʌk.teɪz/

A form of methylenetetrahydrofolate reductase — an enzyme that converts 5,10-methylenetetrahydrofolate into 5-methyltetrahydrofolate, a key step in folate metabolism that supports the body’s methylation cycle and homocysteine processing.

Scrabble 55
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Meanings

nounmethylenetetrahydrofolatereductase (uncountable)
  1. alternativeuncountableAlternative form of methylenetetrahydrofolate reductase.

    Evaluation of thrombophilia disorders established the patient to be heterozygous for methylenetetrahydrofolatereductase C677T gene mutation as the only finding.

    2013 August 23, Paul-Ann D Green et al., “Unilateral adrenal infarction in pregnancy”, in BMJ Case Reports, volume 2013, →DOI
Cite this entry
APA

methylenetetrahydrofolatereductase. (n.d.). In WatkinsX Dictionary. Retrieved November 5, 2026, from https://dictionary.watkinsx.com/word/methylenetetrahydrofolatereductase

MLA

“methylenetetrahydrofolatereductase.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/methylenetetrahydrofolatereductase. Accessed November 5, 2026.

Chicago

WatkinsX Dictionary, s.v. “methylenetetrahydrofolatereductase,” accessed November 5, 2026, https://dictionary.watkinsx.com/word/methylenetetrahydrofolatereductase.

Source: methylenetetrahydrofolatereductase on Wiktionary, CC BY-SA 4.0.