mismigrate

present singular third person mismigrates · participle present mismigrating · participle past mismigrated · past mismigrated

1. To migrate incorrectly.

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   Under these provisions, the germ cell theory paradoxically implies that the biologically more indolent germinomas arise from the most undifferentiated germ cells, whereas the most malignant forms of GCTs (choriocarcinoma and yolk sac tumor) arise from highly differentiated germ cells. That, and the notion that the germ cell theory employs parthenogenesis in humans, and the lack of a plausible explanation of the mechanism through which primordial germ cells mismigrate to the cranial cavity, led to its challenge by Sano and colleagues who proposed the alternative "embryonic cell theory." This suggests that a mismigrational pluripotent embryonic cell (i.e., a stem cell at the blastocyst stage, past the stage of a totipotent stem cell) gives rise to intracranial GCTs.¹¹ Contrary to the germ cell theory, which advocates that all types of GCTs arise from a common cell of origin (primordial germ cell), the embryonic cell theory suggests the involvement of multiple embryonic cells of various stages of embryogenesis.

   2017, Eyas M. Hattab, “Chapter 18: Germ Cell Tumors”, in Arie Perry, Daniel J. Brat, editors, Practical Surgical Neuropathology: A Diagnostic Approach E-Book (Pattern Recognition Series), Elsevier, →ISBN, pages 423-424