missense

M3I1S1S1E1N1S1E1

noun

A damaged DNA sequence that is meaningful but has an incorrect meaning, with the result that its products do not do what they are supposed to do.

UncommonScrabble 10

Meanings

nounmissense (countable and uncountable, plural missenses)

plural missenses

  1. countableuncountablebiologyA damaged DNA sequence that is meaningful but has an incorrect meaning, with the result that its products do not do what they are supposed to do.
verbmissense (third-person singular simple present missenses, present participle missensing, simple past and past participle missensed)

present singular third person missenses · participle present missensing · participle past missensed · past missensed

  1. To sense incorrectly.

    One possibility is that if G6PT is a G6P sensor, it may be missensing the intracellular concentrations and misdirecting further accumulation.

    2012, Stefan Bröer, Carsten A. Wagner, Membrane Transporter Diseases, page 194

Origin

  1. Proto-Indo-European*mey-?
  2. Proto-Indo-European*meyth₂-
  3. Proto-Germanic*missaz
  4. Proto-Germanic*missa-
  5. Proto-West Germanic*missa-
  6. Old Englishmis-
  7. Middle Englishmys-
  8. Englishmis-
  9. Proto-Indo-European*sent-
  10. Proto-Italic*sentiō
  11. Latinsentiō
  12. Latinsēnsu
  13. Proto-Germanic*sinnaz
  14. Frankish*sinn
  15. Vulgar Latin*sennus
  16. Old Frenchsens
  17. Middle Englishsense
  18. Englishsense
  19. Englishmissense

From mis- + sense.

Full word history & related roots →

Rhymes & wordplay

Anagrams

Cite this entry
APA

missense. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/missense

MLA

“missense.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/missense. Accessed November 3, 2026.

Chicago

WatkinsX Dictionary, s.v. “missense,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/missense.

Source: missense on Wiktionary, CC BY-SA 4.0.