Meanings
- uncountablemedicineHeightened responsiveness to sensory input, thought to result from dysfunction in the processing of pain signals by the central nervous system.
Thus, nociplastic pain is linked with, but not synonymous with, central sensitization. Nociplastic pain is a maladaptive nervous system dysfunction associated with altered nociceptive processing and increased responsiveness to subthreshold afferent input^(19,21,26) and is chronic by definition.
2022, Betsy Myers, June Hanks, Management of Common Orthopaedic Disorders, Wolters Kluwer, unnumbered page2 more examples
2019, Mark A. Jones, Darren A. Rivett, Clinical Reasoning in Musculoskeletal Practice, Elsevier, 2nd Edition, E-book Edition, page 40, Nociplastic pain is clearly dysfunctional as it serves no protective benefit to the people experiencing it. Nociplastic pain is significantly disproportionate to any plausible tissue contributions, persists beyond expected tissue healing times and may be recurrent in nature.
2022, Deeba Minhas, Daniel J. Clauw, 88: Fibromyalgia and related syndromes, Marc C. Hochberg, Josef S. Smolen, Michael E. Weinblatt, Michael H. Weisman, Ellen M Gravallese, Desiree van der Heijde (editors), Rheumatology, Elsevier, 8th Edition, page 740, Fibromyalgia (FM) is the prototypical nociplastic pain syndrome.
Synonyms: central sensitisation
Synonyms & antonyms
nounHeightened responsiveness to sensory input, thought to result from dysfunction in the processing of pain signals by the central nervous system.
Translations
German noziplastischer Schmerz, Zentrale Sensitivierung
- noziplastischer Schmerzpain thought to result from dysfunction in pain signal processing
- Zentrale Sensitivierungpain thought to result from dysfunction in pain signal processing
Polish ból nocyplastyczny
- ból nocyplastycznypain thought to result from dysfunction in pain signal processing
Cite this entry
nociplastic pain. (n.d.). In WatkinsX Dictionary. Retrieved November 5, 2026, from https://dictionary.watkinsx.com/word/nociplastic%20pain
“nociplastic pain.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/nociplastic%20pain. Accessed November 5, 2026.
WatkinsX Dictionary, s.v. “nociplastic pain,” accessed November 5, 2026, https://dictionary.watkinsx.com/word/nociplastic%20pain.
Source: nociplastic pain on Wiktionary, CC BY-SA 4.0.