Meanings
plural nonsterols
- Any organic compound that is not a sterol (but typically, having a somewhat similar structure)
Once ubiquitinated, reductase becomes dislocated from ER membranes into the cytosol for degradation by 26 S proteasomes through poorly defined reactions mediated by the AAA-ATPase valosin-containing protein (VCP)/p97 and augmented by the nonsterol isoprenoid geranylgeraniol.
2014 May 24, Lindsey L. Morris et al., “Sequential Actions of the AAA-ATPase Valosin-containing Protein (VCP)/p97 and the Proteasome 19 S Regulatory Particle in Sterol-accelerated, Endoplasmic Reticulum (ER)-associated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase*”, in The Journal of Biological Chemistry, volume 289, →DOI
Origin
Cite this entry
nonsterol. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/nonsterol
“nonsterol.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/nonsterol. Accessed November 4, 2026.
WatkinsX Dictionary, s.v. “nonsterol,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/nonsterol.
Source: nonsterol on Wiktionary, CC BY-SA 4.0.