Meanings
plural oncometabolites
- biochemistryAny metabolite that is associated with a cancer
Due to this pleiotropic function for dysregulating biological events, 2-HG is regarded as an oncometabolite that exerts tumor-inducing actions, and searches for IDH gene mutations have been performed in various types of malignancies [1 ,2 ].
2015 July 11, “Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes”, in PLOS ONE, →DOI
Origin
Cite this entry
oncometabolite. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/oncometabolite
“oncometabolite.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/oncometabolite. Accessed November 3, 2026.
WatkinsX Dictionary, s.v. “oncometabolite,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/oncometabolite.
Source: oncometabolite on Wiktionary, CC BY-SA 4.0.