opioid

O1P3I1O1I1D2
UK/ˈəʊpiɔɪd/

noun

Any of the natural substances, such as an endorphin, released in the body in response to pain; an endogenous opioid.

Less commonScrabble 9

Meanings

nounopioid (plural opioids)

plural opioids

  1. A substance that has effects similar to opium:
    1. medicineAny of the natural substances, such as an endorphin, released in the body in response to pain; an endogenous opioid.

      Mechoulam concluded that our bodies must produce their own cannabinoids — endogenous molecules that, like the native opioids and nicotinelike molecules our bodies also make, engage the cannabinoid receptors throughout the human body.

      2019 May 14, Moises Velasquez-Manoff, “Can CBD Really Do All That?”, in The New York Times Magazine
    2. medicineAny of a group of synthetic compounds that exhibit similarities to the opium alkaloids that occur in nature.

      The number of young children in the US who have died from opioid overdoses has increased significantly, according to a new study on accidental poisonings of children 5 and younger.

      2023 March 8, Jen Christensen, “Young children are increasingly victims of opioid epidemic, study finds”, in CNN

Origin

Attested 1963; from opium + -oid, to distinguish from opiate.

Full word history & related roots →

Translations

Chinese Mandarin 鴉片劑 /鸦片剂
  • 鴉片劑 /鸦片剂 (yāpiànjì)substance that has effects similar to opium
Finnish opioidi
  • opioidisubstance that has effects similar to opium
German Opioid
  • Opioidsubstance that has effects similar to opium
Indonesian opioid
  • opioidsubstance that has effects similar to opium
Māori whakaporehu
  • whakaporehusubstance that has effects similar to opium
Polish opioid
  • opioidsubstance that has effects similar to opium
Spanish opioide
  • opioidesubstance that has effects similar to opium
Swahili opioidi
  • opioidisubstance that has effects similar to opium
Cite this entry
APA

opioid. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/opioid

MLA

“opioid.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/opioid. Accessed November 3, 2026.

Chicago

WatkinsX Dictionary, s.v. “opioid,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/opioid.

Source: opioid on Wiktionary, CC BY-SA 4.0.