perturbagen

plural perturbagens

1. A substance (typically a peptide) designed to disrupt intracellular processes, providing information about the operation of pathways and networks within a cell.

   1 more example

   To address this problem, we have previously proposed a parametrization of perturbagen-target systems in which we characterize each system by its responsiveness (the probability that a perturbagen has an effect on a target) and its uniqueness (the probability that a perturbagen or target is different from others) [ 18 ].

   2015 July 9, Maja Temerinac-Ott, Armaghan W Naik, Robert F Murphy, “Deciding when to stop: efficient experimentation to learn to predict drug-target interactions”, in BMC Bioinformatics, volume 16, →DOI