Meanings
plural polypharmacologies
- The presence of multiple pharmacologies (targets, modes of action etc) in a single drug
While several classes of kinase inhibitors are highly selective (MEK, covalent modifying kinase inhibitors) many possess a vast polypharmacology across the kinome target-scape.
2015 July 16, “Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays”, in PLOS ONE, →DOI
Origin
Cite this entry
polypharmacology. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/polypharmacology
“polypharmacology.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/polypharmacology. Accessed November 4, 2026.
WatkinsX Dictionary, s.v. “polypharmacology,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/polypharmacology.
Source: polypharmacology on Wiktionary, CC BY-SA 4.0.