Meanings
plural prostaspheres
- A spherical cluster of prostate cancer cells
1 more example
Three-dimensional culture studies showed that trabectedin reduced the number and diameter of spheroids of DU145 and PC3 CSCs. Furthermore, we have found that trabectedin disrupted cell-cell interactions via E-cadherin in prostasphere of DU-145 and PC-3 CSCs. Our results showed that trabectedin inhibits cellular proliferation and accelerates apoptotic events in prostate CSCs; and may be a potential effective therapeutic agent against prostate cancer.
2015 October 21, “Enhanced G2/M Arrest, Caspase Related Apoptosis and Reduced E-Cadherin Dependent Intercellular Adhesion by Trabectedin in Prostate Cancer Stem Cells”, in PLOS ONE, →DOI
Origin
Cite this entry
prostasphere. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/prostasphere
“prostasphere.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/prostasphere. Accessed November 3, 2026.
WatkinsX Dictionary, s.v. “prostasphere,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/prostasphere.
Source: prostasphere on Wiktionary, CC BY-SA 4.0.