Meanings
plural pseudopseudohypoparathyroidisms · abbreviation PPHP
- biologyA genetic condition characterized by physical features similar to pseudohypoparathyroidism such as short stature, round facies, and subcutaneous ossifications, but without biochemical abnormalities like calcium or phosphate imbalance, due to normal end-organ responsiveness to parathyroid hormone.
1 more example
Because Gαs is paternally imprinted in certain hormone target tissues, maternal inheritance of AHO leads to multihormone resistance [pseudohypoparathyroidism type 1a (PHP1a)], whereas paternal inheritance leads to AHO alone [pseudopseudohypoparathyroidism (pseudoPHP)]. Classically, the obesity in AHO is described as occurring similarly in both conditions.
2007, Dominique N. Long, Sarah McGuire, Michael A. Levine, Lee S. Weinstein, Emily L. Germain-Lee, Body Mass Index Differences in Pseudohypoparathyroidism Type 1a Versus Pseudopseudohypoparathyroidism May Implicate Paternal Imprinting of Gαs in the Development of Human Obesity: Journal of Clinical Endocrinology & Metabolism, volume 92, number 3, pages 1073–1079Synonyms: pseudoPHP
Synonyms & antonyms
nounA genetic condition characterized by physical features similar to pseudohypoparathyroidism such as short stature, round facies, and subcutaneous ossifications, but without biochemical abnormalities like calcium or phosphate imbalance, due to normal end-organ responsiveness to parathyroid hormone.
Origin
- Ancient Greekψεύδω (pseúdō)
- Ancient Greekψευδής (pseudḗs)
- Middle Englishpseudo-
- Englishpseudo-
- Proto-Indo-European*upó
- Ancient Greekῠ̔πό (hŭpó)
- Ancient Greekὑπο- (hupo-)
- Englishhypo-
- Proto-Indo-European*per-
- Proto-Indo-European*preh₂-
- Proto-Hellenic*pərai
- Ancient Greekπᾰρᾰ́ (părắ)
- Ancient Greekπᾰρᾰ- (pără-)
- Englishpara-
- Proto-Indo-European*dʰwer-
- Proto-Hellenic*tʰurā
- Ancient Greekθῠ́ρᾱ (thŭ́rā)
- Ancient Greekθῠρεός (thŭreós)
- Proto-Indo-European*weyd-
- Proto-Indo-European*wéydos
- Proto-Hellenic*wéidos
- Ancient Greekεἶδος (eîdos)
- Ancient Greekθῠρεοειδής (thŭreoeidḗs)
- New Latinthyreoīdēs
- Englishthyroid
- Englishparathyroid
- Englishhypoparathyroidism
- Englishpseudohypoparathyroidism
- Englishpseudopseudohypoparathyroidism
From pseudo- (“false”) + pseudohypoparathyroidism.
Full word history & related roots →Cite this entry
pseudopseudohypoparathyroidism. (n.d.). In WatkinsX Dictionary. Retrieved November 5, 2026, from https://dictionary.watkinsx.com/word/pseudopseudohypoparathyroidism
“pseudopseudohypoparathyroidism.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/pseudopseudohypoparathyroidism. Accessed November 5, 2026.
WatkinsX Dictionary, s.v. “pseudopseudohypoparathyroidism,” accessed November 5, 2026, https://dictionary.watkinsx.com/word/pseudopseudohypoparathyroidism.
Source: pseudopseudohypoparathyroidism on Wiktionary, CC BY-SA 4.0.