rofecoxib

R1O1F4E1C3O1X8I1B3
US/ˌɹoʊ.fəˈkɑk.sɪb/

noun

A COX-2 inhibitor C₁₇H₁₄O₄S (trademark Vioxx) used to relieve the signs and symptoms of osteoarthritis and rheumatoid arthritis, to manage acute pain in adults, and to treat primary dysmenorrhea but withdrawn from sale by the manufacturer because of its link to cardiovascular events (as heart attack and stroke).

Similar
Vioxx
UncommonScrabble 23
Ask AI about this wordChatGPTClaudePerplexityGoogle AIGrok

Meanings

nounrofecoxib (uncountable)
  1. uncountablemedicineA COX-2 inhibitor C₁₇H₁₄O₄S (trademark Vioxx) used to relieve the signs and symptoms of osteoarthritis and rheumatoid arthritis, to manage acute pain in adults, and to treat primary dysmenorrhea but withdrawn from sale by the manufacturer because of its link to cardiovascular events (as heart attack and stroke).

Synonyms & antonyms

nouna Cox-2 inhibitor (trade name Vioxx) that relieves pain and inflammation without harming the digestive tract; voluntarily withdrawn from the market in 2004

Similar
Vioxx
Broader
Cox-2 inhibitor

Synonym sets from Open English WordNet, CC BY 4.0.

Origin

From rofe- (of unknown origin) + -coxib (“selective cyclo-oxygenase inhibitor”).

Full word history & related roots →
Cite this entry
APA

rofecoxib. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/rofecoxib

MLA

“rofecoxib.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/rofecoxib. Accessed November 3, 2026.

Chicago

WatkinsX Dictionary, s.v. “rofecoxib,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/rofecoxib.

Source: rofecoxib on Wiktionary, CC BY-SA 4.0.