semisynthesize

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verb

To synthesize partially, usually by incorporating natural components.

Scrabble 31
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Meanings

verbsemisynthesize (third-person singular simple present semisynthesizes, present participle semisynthesizing, simple past and past participle semisynthesized)

present singular third person semisynthesizes · participle present semisynthesizing · participle past semisynthesized · past semisynthesized

  1. chemistryTo synthesize partially, usually by incorporating natural components.

    The 1,241st compound that they "semisynthesized" in this way looked particularly promising.

    1977, Harry Filmore Dowling, Fighting Infection: Conquests of the Twentieth Century, page 185
    1 more example

    The EPL (expressed protein ligation, also named intein-mediated protein ligation IPL) technique can be used to semisynthesize proteins from recombinant and synthetic fragments, thus extending the size and complexity of the protein targets available to chemical engineering.

    2007, Marcus A. Hemminga, Lawrence Berliner, ESR Spectroscopy in Membrane Biophysics

Origin

From semi- + synthesize.

Full word history & related roots →
Cite this entry
APA

semisynthesize. (n.d.). In WatkinsX Dictionary. Retrieved November 4, 2026, from https://dictionary.watkinsx.com/word/semisynthesize

MLA

“semisynthesize.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/semisynthesize. Accessed November 4, 2026.

Chicago

WatkinsX Dictionary, s.v. “semisynthesize,” accessed November 4, 2026, https://dictionary.watkinsx.com/word/semisynthesize.

Source: semisynthesize on Wiktionary, CC BY-SA 4.0.