Meanings
plural spectraplakins
- biochemistryAny of a group of exceptionally long, intracellular proteins that have the rare ability to bind to all three cytoskeletal elements: actin, microtubules, and intermediate filaments
1 more example
Thus it is possible that in Schwann cells, Dst is involved in any or all of intermediate filament organization, basement membrane formation and mediation of signaling of specific integrin complexes—none of which are present in OLs. Further explanation may exist for the seemingly disposable nature of neuronal Dst in OLs. In mammals, a second member of the spectraplakin exists: microtubule-actin crosslinking factor 1 (Macf1; variantly actin crosslinking family 7/Acf7).
2016 February 18, “Cytoskeletal Linker Protein Dystonin Is Not Critical to Terminal Oligodendrocyte Differentiation or CNS Myelination”, in PLOS ONE, →DOI
Cite this entry
spectraplakin. (n.d.). In WatkinsX Dictionary. Retrieved November 3, 2026, from https://dictionary.watkinsx.com/word/spectraplakin
“spectraplakin.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/spectraplakin. Accessed November 3, 2026.
WatkinsX Dictionary, s.v. “spectraplakin,” accessed November 3, 2026, https://dictionary.watkinsx.com/word/spectraplakin.
Source: spectraplakin on Wiktionary, CC BY-SA 4.0.